{"id":5592,"date":"2025-08-20T08:59:58","date_gmt":"2025-08-20T01:59:58","guid":{"rendered":"https:\/\/nopphatnguoi.vn\/blog\/hoi-chung-ngu-keo-dai-bi-an-benh-ly-khien-nguoi-benh-ngu-16-tieng-moi-ngay\/"},"modified":"2025-08-20T09:00:12","modified_gmt":"2025-08-20T02:00:12","slug":"hoi-chung-ngu-keo-dai-bi-an-benh-ly-khien-nguoi-benh-ngu-16-tieng-moi-ngay","status":"publish","type":"post","link":"https:\/\/nopphatnguoi.vn\/blog\/hoi-chung-ngu-keo-dai-bi-an-benh-ly-khien-nguoi-benh-ngu-16-tieng-moi-ngay\/","title":{"rendered":"H\u1ed9i ch\u1ee9ng ng\u1ee7 k\u00e9o d\u00e0i: B\u00ed \u1ea9n b\u1ec7nh l\u00fd khi\u1ebfn ng\u01b0\u1eddi b\u1ec7nh ng\u1ee7 16 ti\u1ebfng m\u1ed7i ng\u00e0y"},"content":{"rendered":"<div>\n<p>H&#7897;i ch&#7913;ng Kleine-Levin, m&#7897;t r&#7889;i lo&#7841;n th&#7847;n kinh hi&#7871;m g&#7863;p, &#273;&atilde; thu h&uacute;t s&#7921; quan t&acirc;m c&#7911;a c&#7897;ng &#273;&#7891;ng y h&#7885;c qu&#7889;c t&#7871; do c&aacute;c bi&#7875;u hi&#7879;n l&acirc;m s&agrave;ng ph&#7913;c t&#7841;p v&agrave; &#7843;nh h&#432;&#7903;ng s&acirc;u s&#7855;c &#273;&#7871;n ch&#7845;t l&#432;&#7907;ng cu&#7897;c s&#7889;ng c&#7911;a b&#7879;nh nh&acirc;n. C&ograve;n &#273;&#432;&#7907;c bi&#7871;t &#273;&#7871;n v&#7899;i t&ecirc;n g&#7885;i h&#7897;i ch&#7913;ng n&agrave;ng ng&#7911; ho&#7863;c h&#7897;i ch&#7913;ng ng&#7911; gia &#273;&igrave;nh, t&igrave;nh tr&#7841;ng n&agrave;y g&acirc;y ra c&aacute;c giai &#273;o&#7841;n ng&#7911; d&agrave;i b&#7845;t th&#432;&#7901;ng, k&eacute;o d&agrave;i t&#7915; 16 &#273;&#7871;n 20 gi&#7901; m&#7895;i ng&agrave;y. T&#7927; l&#7879; m&#7855;c h&#7897;i ch&#7913;ng Kleine-Levin r&#7845;t th&#7845;p, &#7843;nh h&#432;&#7903;ng &#273;&#7871;n kho&#7843;ng m&#7897;t &#273;&#7871;n n&#259;m ng&#432;&#7901;i tr&ecirc;n m&#7897;t tri&#7879;u d&acirc;n, v&agrave; cao h&#417;n &#7903; ng&#432;&#7901;i Do Th&aacute;i Ashkenazi.<\/p>\n<figure><img decoding=\"async\" src=\"https:\/\/media.tripmap.vn\/blog-npn\/2025\/08\/hoi-chung-ngu-keo-dai-bi-an-benh-ly-khien-nguoi-benh-ngu-16-tieng-moi-ngay.webp\" alt=\"The exact cause of KLS is unknown, although researchers suggest that it may be genetic or the result of an illness or injury that damages the hypothalamus.\" width=\"100%\"><figcaption>The exact cause of KLS is unknown, although researchers suggest that it may be genetic or the result of an illness or injury that damages the hypothalamus.<\/figcaption><\/figure>\n<p>T&iacute;nh &#273;&#7871;n nay, ch&#7881; c&oacute; kho&#7843;ng 500 tr&#432;&#7901;ng h&#7907;p &#273;&#432;&#7907;c b&aacute;o c&aacute;o tr&ecirc;n c&aacute;c t&#7841;p ch&iacute; y h&#7885;c. S&#7921; hi&#7871;m g&#7863;p c&#7911;a h&#7897;i ch&#7913;ng n&agrave;y kh&ocirc;ng ch&#7881; l&agrave;m cho vi&#7879;c ch&#7849;n &#273;o&aacute;n tr&#7903; n&ecirc;n kh&oacute; kh&#259;n m&agrave; c&ograve;n h&#7841;n ch&#7871; vi&#7879;c nghi&ecirc;n c&#7913;u v&agrave; t&igrave;m ra ph&#432;&#417;ng ph&aacute;p &#273;i&#7873;u tr&#7883; hi&#7879;u qu&#7843;. H&#7897;i ch&#7913;ng Kleine-Levin c&oacute; th&#7875; &#7843;nh h&#432;&#7903;ng &#273;&#7871;n c&#7843; nam v&agrave; n&#7919;, nh&#432;ng 70% s&#7889; ca m&#7855;c l&agrave; nam gi&#7899;i. C&aacute;c tri&#7879;u ch&#7913;ng th&#432;&#7901;ng xu&#7845;t hi&#7879;n &#7903; giai &#273;o&#7841;n v&#7883; th&agrave;nh ni&ecirc;n s&#7899;m v&agrave; k&eacute;o d&agrave;i trung b&igrave;nh 14 n&#259;m, t&#7841;o ra nh&#7919;ng th&aacute;ch th&#7913;c l&acirc;u d&agrave;i cho b&#7879;nh nh&acirc;n v&agrave; gia &#273;&igrave;nh h&#7885;.<\/p>\n<figure><img decoding=\"async\" src=\"https:\/\/media.tripmap.vn\/blog-npn\/2025\/08\/hoi-chung-ngu-keo-dai-bi-an-benh-ly-khien-nguoi-benh-ngu-16-tieng-moi-ngay-2.webp\" alt=\"Episodes average around 10 days but can last for several weeks.\" width=\"100%\"><figcaption>Episodes average around 10 days but can last for several weeks.<\/figcaption><\/figure>\n<p>&#272;&acirc;y l&agrave; m&#7897;t ph&#7847;n c&#7911;a nh&oacute;m r&#7889;i lo&#7841;n qu&aacute; m&#7913;c ng&#7911;, bao g&#7891;m c&#7843; ch&#7913;ng ng&#7911; g&#7853;t. M&#7897;t &#273;&#7907;t b&ugrave;ng ph&aacute;t c&#7911;a h&#7897;i ch&#7913;ng Kleine-Levin &#273;&#432;&#7907;c &#273;&#7883;nh ngh&#297;a l&agrave; c&aacute;c tri&#7879;u ch&#7913;ng k&eacute;o d&agrave;i &iacute;t nh&#7845;t hai ng&agrave;y, trung b&igrave;nh k&eacute;o d&agrave;i kho&#7843;ng 10 ng&agrave;y nh&#432;ng c&oacute; th&#7875; k&eacute;o d&agrave;i h&agrave;ng tu&#7847;n. Trong m&#7897;t s&#7889; tr&#432;&#7901;ng h&#7907;p nghi&ecirc;m tr&#7885;ng, b&#7879;nh nh&acirc;n c&oacute; th&#7875; ng&#7911; li&ecirc;n t&#7909;c t&#7899;i 70 ng&agrave;y. B&ecirc;n c&#7841;nh vi&#7879;c ng&#7911; nhi&#7873;u, c&aacute;c tri&#7879;u ch&#7913;ng kh&aacute;c trong &#273;&#7907;t b&ugrave;ng ph&aacute;t bao g&#7891;m t&igrave;nh tr&#7841;ng &#273;&oacute;i d&#7919; d&#7897;i, &#7843;o gi&aacute;c, v&agrave; ham mu&#7889;n t&igrave;nh d&#7909;c cao.<\/p>\n<p>C&aacute;c tri&#7879;u ch&#7913;ng c&#7911;a h&#7897;i ch&#7913;ng Kleine-Levin r&#7845;t &#273;a d&#7841;ng v&agrave; c&oacute; th&#7875; bao g&#7891;m bu&#7891;n drowsiness c&#7921;c &#273;&#7897;, t&#259;ng c&#7843;m gi&aacute;c th&egrave;m &#259;n, t&#259;ng c&acirc;n, ham mu&#7889;n t&igrave;nh d&#7909;c t&#259;ng cao, &#7843;o gi&aacute;c, thay &#273;&#7893;i h&agrave;nh vi, lo l&#7855;ng ho&#7863;c tr&#7847;m c&#7843;m, v&agrave; m&#7845;t tr&iacute; nh&#7899;. S&#7921; xu&#7845;t hi&#7879;n &#273;&#7897;t ng&#7897;t c&#7911;a c&aacute;c &#273;&#7907;t b&ugrave;ng ph&aacute;t l&agrave;m t&#259;ng nguy c&#417; ch&#7845;n th&#432;&#417;ng, &#273;&#7863;c bi&#7879;t n&#7871;u b&#7879;nh nh&acirc;n v&#7853;n h&agrave;nh xe c&#417; gi&#7899;i ho&#7863;c m&aacute;y m&oacute;c. V&igrave; v&#7853;y, ng&#432;&#7901;i m&#7855;c h&#7897;i ch&#7913;ng n&agrave;y &#273;&#432;&#7907;c khuy&ecirc;n &#7903; nh&agrave; trong m&#7897;t m&ocirc;i tr&#432;&#7901;ng an to&agrave;n trong c&aacute;c &#273;&#7907;t b&ugrave;ng ph&aacute;t &#273;&#7875; gi&#7843;m thi&#7875;u r&#7911;i ro.<\/p>\n<p>Nguy&ecirc;n nh&acirc;n ch&iacute;nh x&aacute;c c&#7911;a h&#7897;i ch&#7913;ng Kleine-Levin v&#7851;n ch&#432;a &#273;&#432;&#7907;c hi&#7875;u r&otilde;. C&aacute;c nh&agrave; nghi&ecirc;n c&#7913;u cho r&#7857;ng c&oacute; th&#7875; do y&#7871;u t&#7889; di truy&#7873;n ho&#7863;c do m&#7897;t c&#259;n b&#7879;nh, ch&#7845;n th&#432;&#417;ng g&acirc;y t&#7893;n th&#432;&#417;ng v&ugrave;ng d&#432;&#7899;i &#273;&#7891;i &#8211; ph&#7847;n n&atilde;o ch&#7883;u tr&aacute;ch nhi&#7879;m &#273;i&#7873;u ch&#7881;nh gi&#7845;c ng&#7911;. M&#7897;t s&#7889; tr&#432;&#7901;ng h&#7907;p c&oacute; th&#7875; &#273;&#432;&#7907;c k&iacute;ch ho&#7841;t b&#7903;i nhi&#7877;m tr&ugrave;ng, s&#7917; d&#7909;ng ch&#7845;t, sang ch&#7845;n &#273;&#7847;u, g&#7855;ng s&#7913;c th&#7875; ch&#7845;t ho&#7863;c c&#259;ng th&#7859;ng. Nh&#7919;ng y&#7871;u t&#7889; n&agrave;y c&oacute; th&#7875; &#273;&oacute;ng vai tr&ograve; trong vi&#7879;c k&iacute;ch ho&#7841;t c&aacute;c &#273;&#7907;t b&ugrave;ng ph&aacute;t, nh&#432;ng c&#417; ch&#7871; ch&iacute;nh x&aacute;c v&#7851;n c&ograve;n l&agrave; m&#7897;t b&iacute; &#7849;n.<\/p>\n<p>Trong c&aacute;c &#273;&#7907;t b&ugrave;ng ph&aacute;t, tr&iacute; nh&#7899; c&#7911;a b&#7879;nh nh&acirc;n b&#7883; h&#7841;n ch&#7871;. H&#7885; c&oacute; th&#7875; th&#7921;c hi&#7879;n c&aacute;c h&agrave;nh &#273;&#7897;ng c&#417; b&#7843;n nh&#432; &#259;n v&agrave; s&#7917; d&#7909;ng nh&agrave; v&#7879; sinh, nh&#432;ng do s&#7921; m&#7879;t m&#7887;i c&#7921;c &#273;&#7897;, h&#7885; g&#7863;p kh&oacute; kh&#259;n v&#7899;i c&aacute;c ch&#7913;c n&#259;ng th&#7875; ch&#7845;t ngo&agrave;i c&aacute;c h&agrave;nh vi c&#417; b&#7843;n n&agrave;y. &#272;i&#7873;u n&agrave;y g&acirc;y ra kh&ocirc;ng ch&#7881; s&#7921; b&#7845;t ti&#7879;n m&agrave; c&ograve;n &#7843;nh h&#432;&#7903;ng &#273;&#7871;n s&#7921; &#273;&#7897;c l&#7853;p c&#7911;a b&#7879;nh nh&acirc;n.<\/p>\n<p>&#272;i&#7873;u tr&#7883; h&#7897;i ch&#7913;ng Kleine-Levin th&#432;&#7901;ng bao g&#7891;m c&aacute;c lo&#7841;i thu&#7889;c nh&#432; lithium, steroid, v&agrave; thu&#7889;c k&iacute;ch th&iacute;ch &#273;&#7875; gi&#7843;m t&#7847;n su&#7845;t, th&#7901;i gian, v&agrave; m&#7913;c &#273;&#7897; nghi&ecirc;m tr&#7885;ng c&#7911;a c&aacute;c &#273;&#7907;t b&ugrave;ng ph&aacute;t. Tr&#7883; li&#7879;u t&acirc;m l&yacute; c&#361;ng &#273;&#432;&#7907;c khuy&#7871;n ngh&#7883; c&ugrave;ng v&#7899;i c&aacute;c ph&#432;&#417;ng ph&aacute;p &#273;i&#7873;u tr&#7883; n&agrave;y &#273;&#7875; gi&uacute;p b&#7879;nh nh&acirc;n ki&#7875;m so&aacute;t c&aacute;c tri&#7879;u ch&#7913;ng nh&#432; ham mu&#7889;n t&igrave;nh d&#7909;c qu&aacute; m&#7913;c, lo l&#7855;ng, v&agrave; tr&#7847;m c&#7843;m. M&#7863;c d&ugrave; vi&#7879;c &#273;i&#7873;u tr&#7883; c&oacute; th&#7875; gi&uacute;p gi&#7843;m thi&#7875;u c&aacute;c tri&#7879;u ch&#7913;ng, nh&#432;ng vi&#7879;c qu&#7843;n l&yacute; h&#7897;i ch&#7913;ng Kleine-Levin v&#7851;n l&agrave; m&#7897;t th&aacute;ch th&#7913;c l&#7899;n &#273;&#7889;i v&#7899;i c&#7843; b&#7879;nh nh&acirc;n v&agrave; c&aacute;c chuy&ecirc;n gia y t&#7871;.<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>H\u1ed9i ch\u1ee9ng Kleine-Levin (KLS) l\u00e0 m\u1ed9t r\u1ed1i lo\u1ea1n th\u1ea7n kinh hi\u1ebfm g\u1eb7p khi\u1ebfn ng\u01b0\u1eddi m\u1eafc ng\u1ee7 trong th\u1eddi gian d\u00e0i, l\u00ean \u0111\u1ebfn 16 \u0111\u1ebfn 20 gi\u1edd m\u1ed7i ng\u00e0y. Nguy\u00ean nh\u00e2n ch\u00ednh x\u00e1c c\u1ee7a KLS kh\u00f4ng r\u00f5 r\u00e0ng, nh\u01b0ng \u0111\u01b0\u1ee3c cho l\u00e0 do b\u1ec7nh t\u1eadt ho\u1eb7c ch\u1ea5n th\u01b0\u01a1ng l\u00e0m t\u1ed5n th\u01b0\u01a1ng v\u00f9ng d\u01b0\u1edbi \u0111\u1ed3i, ph\u1ea7n n\u00e3o ch\u1ecbu tr\u00e1ch nhi\u1ec7m \u0111i\u1ec1u ch\u1ec9nh gi\u1ea5c ng\u1ee7. C\u00e1c \u0111\u1ee3t KLS c\u00f3 th\u1ec3 x\u1ea3y ra \u0111\u1ed9t ng\u1ed9t v\u00e0 c\u00f3 h\u1eadu qu\u1ea3 nghi\u00eam tr\u1ecdng cho b\u1ec7nh nh\u00e2n, bao g\u1ed3m m\u1ea5t tr\u00ed nh\u1edb, kh\u00f3 kh\u0103n v\u1edbi ch\u1ee9c n\u0103ng th\u1ec3 ch\u1ea5t v\u00e0 kh\u00f3 kh\u0103n trong m\u1ed1i quan h\u1ec7.<\/p>\n","protected":false},"author":1,"featured_media":5595,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3],"tags":[4401,5406,4773,5407,580],"class_list":["post-5592","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-thoi-su","tag-giac-ngu","tag-hoi-chung-kleine-levin","tag-nao-bo","tag-roi-loan-than-kinh","tag-suc-khoe"],"_links":{"self":[{"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/posts\/5592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/comments?post=5592"}],"version-history":[{"count":0,"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/posts\/5592\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/media\/5595"}],"wp:attachment":[{"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/media?parent=5592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/categories?post=5592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nopphatnguoi.vn\/blog\/wp-json\/wp\/v2\/tags?post=5592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}